منابع مشابه
Global Screening for Human Viral Pathogens
We propose a system for continuing surveillance of viral pathogens circulating in large human populations. We base this system on the physical isolation of viruses from large pooled samples of human serum and plasma (e.g., discarded specimens from diagnostic laboratories), followed by shotgun sequencing of the resulting genomes. The technology for concentrating virions from 100-L volumes was de...
متن کاملDiagnosis of plant viral pathogens
In the last ten years there has been an explosion in plant virus outbreaks, because of either direct or indirect activities of humans. The ease of transporting plant materials and virus vectors, and collecting relatives of crop plants from the wild, has spread viruses widely throughout the world. The most important step in managing a virus disease is correct identification. Tests for diagnosis ...
متن کاملViral Pathogens in Multiple Sclerosis
P HYSICIANS AND PATIENTS HAVE ALWAYS HAD A great fascination with the invisible pathogen. Koch’s criteria, set out as early as 1882, have generally been ignored, that is, a microorganism must be (1) present in every case of the disease and (2) isolated from the host with the disease and grown in pure culture, (3) the specific disease must be reproduced when a pure culture of the microbe is inoc...
متن کاملViral diagnosis in Indian livestock using customized microarray chips
Viral diagnosis in Indian livestock using customized microarray chips is gaining momentum in recent years. Hence, it is possible to design customized microarray chip for viruses infecting livestock in India. Customized microarray chips identified Bovine herpes virus-1 (BHV-1), Canine Adeno Virus-1 (CAV-1), and Canine Parvo Virus-2 (CPV-2) in clinical samples. Microarray identified specific prob...
متن کاملDevelopment of high-content imaging assays for lethal viral pathogens.
Filoviruses such as Ebola (EBOV) and Marburg (MARV) are single-stranded negative sense RNA viruses that cause acute hemorrhagic fever with high mortality rates. Currently, there are no licensed vaccines or therapeutics to counter filovirus infections in humans. The development of higher throughput/high-content primary screening assays followed by validation using the low-throughput traditional ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genome Biology
سال: 2002
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20021113-01